Article
Adipose Stromal Vascular Fraction-Mediated Improvements at Late-Stage Disease in a Murine Model of Multiple Sclerosis.
Stem cells (Dayton, Ohio) - 1 Feb 2017
Bowles Annie C, Strong Amy L, Wise Rachel M, Thomas Robert C, Gerstein Brittany Y, Dutreil Maria F, Hunter Ryan S, Gimble Jeffrey M, Bunnell Bruce A
Abstract excerpt
Multiple sclerosis (MS) is a common neurodegenerative disease and remains an unmet clinical challenge. In MS, an autoimmune response leads to immune cell infiltration, inflammation, demyelination, and lesions in central nervous system (CNS) tissues resulting in tremors, fatigue, and progressive loss of motor function. These pathologic hallmarks are effectively reproduced in the murine experimental autoimmune...
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