Article
Acyclovir-resistant HSV-1 isolates among immunocompromised patients in southern Taiwan: Low prevalence and novel mutations.
Journal of medical virology - 1 Aug 2023
Kuo Jhao-You, Yeh Chun-Sheng, Wang Shih-Min, Chen Shun-Hua, Wang Jen-Ren, Chen Tsai-Yun, Tsai Huey-Pin
Abstract excerpt
Herpes simplex virus type 1 (HSV-1) can establish latency in humans and easily relapse in immunocompromised patients, with significant mortality. Treatment with acyclovir (ACV) can result in the emergence of HSV resistance. A total of 440 frozen HSV-1 isolates collected from 318 patients from January 2014 to July 2019 were obtained from National Cheng Kung University Hospital in southern Taiwan. These 440...
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