Article
Trans-ancestry meta-analysis of genome wide association studies of inhibitory control.
Molecular psychiatry - 1 Oct 2023
Arnatkeviciute Aurina, Lemire Mathieu, Morrison Claire, Mooney Michael, Ryabinin Peter, Roslin Nicole M, Nikolas Molly, Coxon James, Tiego Jeggan, Hawi Ziarih, Fornito Alex, Henrik Walter, Martinot Jean-Luc, Martinot Marie-Laure Paillère, Artiges Eric, Garavan Hugh, Nigg Joel, Friedman Naomi P, Burton Christie, Schachar Russell, Crosbie Jennifer, Bellgrove Mark A
Abstract excerpt
Deficits in effective executive function, including inhibitory control are associated with risk for a number of psychiatric disorders and significantly impact everyday functioning. These complex traits have been proposed to serve as endophenotypes, however, their genetic architecture is not yet well understood. To identify the common genetic variation associated with inhibitory control in the general population...
Topics
- Humans
- Genome-Wide Association Study
- Schizophrenia
- Executive Function
- Multifactorial Inheritance
- Endophenotypes
- Polymorphism, Single Nucleotide
- Genetic Predisposition to Disease