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Article

Clinical Implication of HER2 Aberration in Patients With Metastatic Cancer Using Next-Generation Sequencing: A Pan-Tumor Analysis.

JCO precision oncology - 1 Jul 2023

Jung Jaeyun, Kim Seung Tae, Ko Jihoon, Hong Jung Yong, Park Joon Oh, Ha Sang Yun, Lee Jeeyun

Abstract excerpt

PURPOSE: Human epidermal growth factor receptor 2 (HER2) protein expression or gene amplification is a significant predictive biomarker for identifying patients with cancer, who may benefit from HER2-targeted therapy. The aim of this study was to survey the proportion of patients who had HER2 aberration and to investigate the correlation between HER2 amplification and HER2 overexpression in immunohistochemistry...

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PMID: 37499191
DOI: 10.1200/PO.22.00537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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