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Article

Vitamin D3 suppresses the cholesterol homeostasis pathway in patient‐derived glioma cell lines

25 Jul 2023

Abstract excerpt

Glioblastoma is one of the most common malignant brain tumors. Vitamin D, primarily its hormonally active form calcitriol, has been reported to have anti-cancer activity. In the present study, we used patient-derived glioma cell lines to examine the effect of vitamin D3 and calcitriol on glioblastoma. Surprisingly, vitamin D3 showed a more significant inhibitory effect than calcitriol on cell viability and...

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PMID: 37489660
DOI: 10.1002/2211-5463.13679

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