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The Role of Sperm Centrioles in Human Reproduction – The Known and the Unknown

1 Oct 2019

Abstract excerpt

Each human spermatozoon contains two remodeled centrioles that it contributes to the zygote. There, the centrioles reconstitute a centrosome that assembles the sperm aster and participate in pronuclei migration and cleavage. Thus, centriole abnormalities may be a cause of male factor infertility and failure to carry pregnancy to term. However, the precise mechanisms by which sperm centrioles contribute to...

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PMID: 31632960
DOI: 10.3389/fcell.2019.00188

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