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Article

Apoptotic variants as predictors of risk of oropharyngeal cancer recurrence after definitive radiotherapy.

International journal of cancer - 15 Nov 2015

Zhang Fenghua, Sturgis Erich M, Sun Yan, Zhang Yang, Wei Qingyi, Zhang Caiyun, Zheng Hongliang, Li Guojun

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in the promoter region of FAS and FASLG may alter their transcriptional activity. Thus, we determined the associations between four FAS and FASLG promoter variants (FAS1377G>A, rs2234767; 670A>G, rs1800682; FASLG844T>C, rs763110 and 124A>G, rs5030772) and the risk of recurrence of squamous cell carcinoma of the oropharynx (SCCOP). We evaluated the associations between FAS...

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Share to Carcinoma, Squamous Cell
Share to Cohort Studies
Share to Fas Ligand Protein
Share to fas Receptor
Share to Neoplasm Recurrence, Local
Share to Oropharyngeal Neoplasms
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Source

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Identifiers

PMID: 25976983
DOI: 10.1002/ijc.29604
PMCID: PMC4575831

Genes

FAS
FASLG

Provenance

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