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Article

Feasibility of probe washing after stereotactic needle biopsy as a novel technique for developing cell lines and xenografts of H3 K27-altered diffuse midline gliomas.

Journal of neurosurgery. Pediatrics - 1 Oct 2023

Rechberger Julian S, Zhang Liang, Ge Jizhi, Nesvick Cody L, Miller Kai J, Daniels David J

Abstract excerpt

H3 K27-altered diffuse midline gliomas (DMGs) are frequently biopsied to obtain tissue diagnosis, inform clinical decision-making, and determine clinical trial eligibility. Tissue yield from biopsies is typically low, leaving little material available for research. To advance understanding of disease biology and promote preclinical testing of novel therapeutics, collecting viable cellular material from...

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Identifiers

PMID: 37486856
DOI: 10.3171/2023.5.PEDS22557
PMCID: PMC11079861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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