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Downregulation of MAL2 inhibits breast cancer progression through regulating β-catenin/c-Myc axis

21 Jul 2023

Abstract excerpt

PURPOSE: Myelin and lymphocyte protein 2 (MAL2) is mainly involved in endocytosis under physiological conditions and mediates the transport of materials across the membranes of cell and organelle. It has been reported that MAL2 is significantly upregulated in diverse cancers. This study aimed to investigate the role of MAL2 in breast cancer (BC). METHODS: Bioinformatics analysis and Immunohistochemical assay were...

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PMID: 37480012
DOI: 10.1186/s12935-023-02993-9

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