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Article

Signaling pathway dysregulation in breast cancer.

Oncotarget - 13 Mar 2025

Ryspayeva Dinara, Seyhan Attila A, MacDonald William J, Purcell Connor, Roady Tyler J, Ghandali Maryam, Verovkina Nataliia, El-Deiry Wafik S, Taylor Martin S, Graff Stephanie L

Abstract excerpt

This article provides a comprehensive analysis of the signaling pathways implicated in breast cancer (BC), the most prevalent malignancy among women and a leading cause of cancer-related mortality globally. Special emphasis is placed on the structural dynamics of protein complexes that are integral to the regulation of these signaling cascades. Dysregulation of cellular signaling is a fundamental aspect of BC...

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Identifiers

PMID: 40080721
DOI: 10.18632/oncotarget.28701
PMCID: PMC11906143

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