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Article

Plasticity of circulating tumor cells in small cell lung cancer

21 Jul 2023

Abstract excerpt

Small cell lung cancer (SCLC) is an aggressive neuroendocrine tumor with low five-year survival rates. Recently described molecular phenotypes of SCLC exhibit differential vulnerabilities heralding potential for stratified treatment. Whilst tumor biopsy in SCLC is challenging, circulating tumor cells in the liquid biopsy are prevalent and can be repeatedly sampled accommodating the dynamic plasticity of SCLC...

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PMID: 37479829
DOI: 10.1038/s41598-023-38881-5

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