Article

scSTAR2: a multiomics integration algorithm to reveal disease-specific cellular signatures by bridging single-cell resolution features and clinical metadata

2025-08-15

Abstract excerpt

Single-cell techniques, pivotal in characterizing intricate cell and spatial structures within tissues, face challenges in contextualizing clinical phenotypes. Currently, most investigations of the clinical phenotype related cell/spatial heterogeneities relied on the phenotype information from single-cell data. However, a wealth of underutilized clinical metadata exists within conventional bulk sequencing data. Cu...

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Literature Corpus work: 347b07a7-6e99-5fba-ad49-3f2e1be1e834
DOI: 10.1101/2025.08.12.669818

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