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Article

Transformation of a chronic myeloproliferative neoplasm to acute myelogenous leukemia: does anything work?

Current hematologic malignancy reports - 1 Mar 2012

Kundranda Madappa N, Tibes Raoul, Mesa Ruben A

Abstract excerpt

The BCR/ABL-negative myeloproliferative neoplasms (MPNs) of essential thrombocythemia, polycythemia vera, and primary myelofibrosis, over the natural course of their disease, have an increasing predisposition to transform to overt acute myeloid leukemia (AML)-most appropriately referred to as MPN-blast phase (MPN-BP). Although this transformation is a rare event, once AML has occurred, it is associated with a...

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Source

Identifiers

PMID: 22170483
DOI: 10.1007/s11899-011-0107-9

Genes

BCR
JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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