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Article

Dysregulation of TMEM16A impairs oviductal transport of embryos

17 Jul 2023

Abstract excerpt

The ion channel protein TMEM16A is expressed in the epithelium and smooth muscle of the human fallopian tube and is upregulated in patients with tubal pregnancy. TMEM16A is involved in regulating the smooth muscle contraction and the cilia beating. Dysregulated TMEM16A may result in embryo retention in the oviduct and delayed early embryo development. Our study reveals a new regulatory point for embryo transport...

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PMID: 37458439
DOI: 10.1152/ajpcell.00031.2023

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