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Article

BRAF testing modalities in histiocytic disorders: Comparative analysis and proposed testing algorithm.

American journal of clinical pathology - 2 Nov 2023

Acosta-Medina Aldo A, Abeykoon Jithma P, Go Ronald S, Goyal Gaurav, Ravindran Aishwarya, Schram Susan M, Rech Karen L

Abstract excerpt

OBJECTIVES: Understanding of histiocytic disorders has been revolutionized by demonstration of mitogen-activated protein kinase (MAPK) pathway mutations, most commonly BRAFV600E. The optimal testing strategy to assess BRAFV600E is unknown. We aimed to compare performance of testing modalities, to propose a framework for evaluation of BRAFV600E mutation status in histiocytic disorders. METHODS: We retrospectively...

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PMID: 37458275
DOI: 10.1093/ajcp/aqad076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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