Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress

Abstract excerpt

Introduction: The Unfolded Protein Response, a mechanism triggered by the cell in response to Endoplasmic reticulum stress, is linked to inflammatory responses. Our aim was to identify novel Unfolded Protein Response-mechanisms that might be involved in triggering or perpetuating the inflammatory response carried out by the Intestinal Epithelial Cells in the context of Inflammatory Bowel Disease. Methods: We...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Advanced Glycation End Products research
• Share to Autophagy in Disease and Therapy
• Share to Endoplasmic Reticulum Stress and Disease