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Gene-repaired iPS cells as novel approach for patient with osteogenesis imperfecta

30 Jun 2023

Abstract excerpt

Introduction: The benefits of patient’s specific cell/gene therapy have been reported in relation to numerous genetic related disorders including osteogenesis imperfecta (OI). In osteogenesis imperfecta particularly also a drug therapy based on the administration of bisphosphonates partially helped to ease the symptoms. Methods: In this controlled trial, fibroblasts derived from patient diagnosed with OI type II...

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PMID: 37456734
DOI: 10.3389/fbioe.2023.1205122

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