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Curative Cell and Gene Therapy for Osteogenesis Imperfecta

1 Dec 2020

Abstract excerpt

Osteogenesis imperfecta (OI) describes a series of genetic bone fragility disorders that can have a substantive impact on patient quality of life. The multidisciplinary approach to management of children and adults with OI primarily involves the administration of antiresorptive medication, allied health (physiotherapy and occupational therapy), and orthopedic surgery. However, advances in gene editing technology...

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PMID: 35306687
DOI: 10.1002/jbmr.4549

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