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Polymeric epitope-based vaccine induces protective immunity against group A Streptococcus

14 Jul 2023

Abstract excerpt

Group A Streptococcus (Strep A) is a life-threatening human pathogen with no licensed vaccine. Here, we used a biopolymer particle (BP) approach to display repeats of Strep A vaccine candidate peptides p*17 and K4S2 derived from M and non-M protein, respectively. BPs densely displaying both peptides (BP-p*17-S2) were successfully assembled in one-step inside an engineered endotoxin-free Escherichia coli strain....

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Share to Bacterial Identification and Susceptibility Testing
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PMID: 37452052
DOI: 10.1038/s41541-023-00695-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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