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Article

Epstein–Barr virus and genetic risk variants as determinants of T-bet+ B cell-driven autoimmune diseases

12 Jul 2023

Abstract excerpt

B cells expressing the transcription factor T-bet are found to have a protective role in viral infections, but are also considered major players in the onset of different types of autoimmune diseases. Currently, the exact mechanisms driving such ‘atypical’ memory B cells to contribute to protective immunity or autoimmunity are unclear. In addition to general autoimmune-related factors including sex and age, the...

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PMID: 37451321
DOI: 10.1016/j.imlet.2023.07.006

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