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Article

SLO3: A Conserved Regulator of Sperm Membrane Potential

7 Jul 2023

Abstract excerpt

Sperm cells must undergo a complex maturation process after ejaculation to be able to fertilize an egg. One component of this maturation is hyperpolarization of the membrane potential to a more negative value. The ion channel responsible for this hyperpolarization, SLO3, was first cloned in 1998, and since then much progress has been made to determine how the channel is regulated and how its function intertwines...

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PMID: 37446382
DOI: 10.3390/ijms241311205

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