Article
Consequences of asymmetric mutational pressure for the dynamic of linear B-cell epitopes repertoire of influenza a virus neuraminidase rearrangement.
Bio Systems - 1 Sept 2023
Khrustalev Vladislav Victorovich, Stojarov Aleksander Nicolaevich, Shen Chenguang, Khrustaleva Tatyana Aleksandrovna
Abstract excerpt
Full-length nucleotide sequences of avian influenza A virus neuraminidase coding region (20,631 sequences) were analyzed and compared with those isolated from viruses infecting human and swine (63,750 sequences). If in fourfold degenerate sites there is asymmetric A-bias that may be more or less asymmetric depending on the type of neuraminidase and the host, than in twofold degenerate sites from third codon...
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