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Article

Roles of ABCA1 in cancer (Review)

19 Aug 2022

Abstract excerpt

Studies have indicated that anticancer drugs targeting cholesterol metabolism have clinical significance. From the perspective of the mechanism of cholesterol excretion from cells, ATP-binding cassette (ABC)A1 has an essential role that cannot be ignored. ABCA1 is located on the cell membrane and able to mediate the efflux of lipids, such as intracellular cholesterol, thereby initiating reverse cholesterol...

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Cancer, Lipids, and Metabolism
Cholesterol and Lipid Metabolism
Drug Transport and Resistance Mechanisms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36072007
DOI: 10.3892/ol.2022.13469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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