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Article

A Single-Site Mutation Tunes Fluorescence and Chromophorylation of an Orange Fluorescent Cyanobacteriochrome.

Chembiochem : a European journal of chemical biology - 4 Oct 2023

Janis Makena K, Zou Wenping, Zastrow Melissa L

Abstract excerpt

Cyanobacteriochrome (CBCR) cGMP-specific phosphodiesterase, adenylyl cyclase, and FhlA (GAF) domains bind bilin cofactors to confer sensory wavelengths important for various cyanobacterial photosensory processes. Many isolated GAF domains autocatalytically bind bilins, including the third GAF domain of CBCR Slr1393 from Synechocystis sp. PCC6803, which binds phycoerythrobilin (PEB) to yield a bright orange...

Topics

Escherichia coli
Fluorescence
Synechocystis
Adenylyl Cyclases
Mutation
Bacterial Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37423892
DOI: 10.1002/cbic.202300358
PMCID: PMC10653908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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