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Clinical and genomic insights into persistent carbapenem-resistant Klebsiella pneumoniae bacteremia: risk factors, resistance mechanisms, and treatment challenges

18 Aug 2025

Abstract excerpt

INTRODUCTION: Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major cause of nosocomial infections with high mortality rates. Persistent bacteremia, indicative of treatment failure, poses significant clinical challenges. This study aimed to identify clinical parameters for persistent CRKP bacteremia while exploring microbial and genetic characteristics. MATERIALS AND METHODS: A case-control study was...

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PMID: 40835109
DOI: 10.1016/j.bj.2025.100905

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