Article
Variations in Genes Encoding Human Papillomavirus Binding Receptors and Susceptibility to Cervical Precancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2023
Mukherjee Amrita, Ye Yuanfan, Wiener Howard W, Kuniholm Mark H, Minkoff Howard, Michel Kate, Palefsky Joel, D'Souza Gypsyamber, Rahangdale Lisa, Butler Kenneth R, Kempf Mirjam-Colette, Sudenga Staci L, Aouizerat Bradley E, Ojesina Akinyemi I, Shrestha Sadeep
Abstract excerpt
BACKGROUND: Cervical cancer oncogenesis starts with human papillomavirus (HPV) cell entry after binding to host cell surface receptors; however, the mechanism is not fully known. We examined polymorphisms in receptor genes hypothesized to be necessary for HPV cell entry and assessed their associations with clinical progression to precancer. METHODS: African American women (N = 1,728) from the MACS/WIHS Combined...
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