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Article

Long-Term Prevalence of Systolic Dysfunction in MYBPC3 Versus MYH7-Related Hypertrophic Cardiomyopathy.

Circulation. Genomic and precision medicine - 1 Aug 2023

Beltrami Matteo, Fedele Elisa, Fumagalli Carlo, Mazzarotto Francesco, Girolami Francesca, Ferrantini Cecilia, Coppini Raffaele, Tofani Lorenzo, Bertaccini Bruno, Poggesi Corrado, Olivotto Iacopo

Abstract excerpt

BACKGROUND: The 2 sarcomere genes most commonly associated with hypertrophic cardiomyopathy (HCM), MYBPC3 (myosin-binding protein C3) and MYH7 (β-myosin heavy chain), are indistinguishable at presentation, and genotype-phenotype correlations have been elusive. Based on molecular and pathophysiological differences, however, it is plausible to hypothesize a different behavior in myocardial performance, impacting...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 37409452
DOI: 10.1161/CIRCGEN.122.003832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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