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Article

Clinical outcomes associated with sarcomere mutations in hypertrophic cardiomyopathy: a meta-analysis on 7675 individuals.

Clinical research in cardiology : official journal of the German Cardiac Society - 1 Jan 2018

Sedaghat-Hamedani Farbod, Kayvanpour Elham, Tugrul Oguz Firat, Lai Alan, Amr Ali, Haas Jan, Proctor Tanja, Ehlermann Philipp, Jensen Katrin, Katus Hugo A, Meder Benjamin

Abstract excerpt

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease, which goes along with increased risk for sudden cardiac death (SCD). Despite the knowledge about the different causal genes, the relationship between individual genotypes and phenotypes is incomplete. METHODS AND RESULTS: We retrieved PubMed/Medline literatures on genotype-phenotype associations in patients with HCM...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28840316
DOI: 10.1007/s00392-017-1155-5

Genes

MYH7
MYBPC3
SCD
TNNT2
TNNI3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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