Article
Lack of Phenotypic Differences by Cardiovascular Magnetic Resonance Imaging in MYH7 (β-Myosin Heavy Chain)- Versus MYBPC3 (Myosin-Binding Protein C)-Related Hypertrophic Cardiomyopathy.
Circulation. Cardiovascular imaging - 1 Feb 2017
Weissler-Snir Adaya, Hindieh Waseem, Gruner Christiane, Fourey Dana, Appelbaum Evan, Rowin Ethan, Care Melanie, Lesser John R, Haas Tammy S, Udelson James E, Manning Warren J, Olivotto Iacopo, Tomberli Benedetta, Maron Barry J, Maron Martin S, Crean Andrew M, Rakowski Harry, Chan Raymond H
Abstract excerpt
BACKGROUND: The 2 most commonly affected genes in hypertrophic cardiomyopathy (HCM) are MYH7 (β-myosin heavy chain) and MYBPC3 (β-myosin-binding protein C). Phenotypic differences between patients with mutations in these 2 genes have been inconsistent. Scarce data exist on the genotype-phenotype association as assessed by tomographic imaging using cardiac magnetic resonance imaging. METHODS AND RESULTS: Cardiac...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.