Article
Association of iron homeostasis biomarkers in type 2 diabetes and glycaemic traits: a bidirectional two-sample Mendelian randomization study.
International journal of epidemiology - 25 Dec 2023
Liang Ying, Luo Shan, Wong Tommy Hon Ting, He Baoting, Schooling C Mary, Au Yeung Shiu Lun
Abstract excerpt
BACKGROUND: Mendelian randomization (MR) studies show iron positively associated with type 2 diabetes (T2D) but included potentially biasing hereditary haemochromatosis variants and did not assess reverse causality. METHODS: We assessed the relation of iron homeostasis with T2D and glycaemic traits bidirectionally, using genome-wide association studies (GWAS) of iron homeostasis biomarkers [ferritin, serum iron,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
