Article
Type 2 Diabetes, Metabolic Traits, and Risk of Heart Failure: A Mendelian Randomization Study.
Diabetes care - 1 Jul 2021
Mordi Ify R, Lumbers R Thomas, Palmer Colin N A, Pearson Ewan R, Sattar Naveed, Holmes Michael V, Lang Chim C
Abstract excerpt
OBJECTIVE: The aim of this study was to use Mendelian randomization (MR) techniques to estimate the causal relationships between genetic liability to type 2 diabetes (T2D), glycemic traits, and risk of heart failure (HF). RESEARCH DESIGN AND METHODS: Summary-level data were obtained from genome-wide association studies of T2D, insulin resistance (IR), glycated hemoglobin, fasting insulin and glucose, and HF. MR...
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