Article
Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?
Human molecular genetics - 15 May 2017
Raffield Laura M, Louie Tin, Sofer Tamar, Jain Deepti, Ipp Eli, Taylor Kent D, Papanicolaou George J, Avilés-Santa Larissa, Lange Leslie A, Laurie Cathy C, Conomos Matthew P, Thornton Timothy A, Chen Yii-Der Ida, Qi Qibin, Cotler Scott, Thyagarajan Bharat, Schneiderman Neil, Rotter Jerome I, Reiner Alex P, Lin Henry J
Abstract excerpt
Genetic variants contribute to normal variation of iron-related traits and may also cause clinical syndromes of iron deficiency or excess. Iron overload and deficiency can adversely affect human health. For example, elevated iron storage is associated with increased diabetes risk, although mechanisms are still being investigated. We conducted the first genome-wide association study of serum iron, total iron...
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