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Metabolic disorders induced by PNPLA3 and TM6SF2 gene variants affect chronic kidney disease in patients infected with non-genotype 3 hepatitis C virus.

Lipids in health and disease - 3 Jul 2023

Liu Jia, Qi Wenqian, Wang Song, Zhang Yonggui, Wang Xu, Sun Derong, Xu Yanhui, Shi Jingyi, Duan Honglei, Zhang Qian, Wang Hongguang, Wang Jiangbin

Abstract excerpt

BACKGROUND: Patients with chronic hepatitis C virus (HCV) infections differ in their risk for metabolic disorders and chronic kidney disease (CKD). The aim of this study was to investigate the effect of metabolic disorders induced by genetic factors on CKD in HCV-infected patients. METHODS: Patients with chronic non-genotype 3 HCV infection with or without CKD were examined. PNPLA3 and TM6SF2 variants were...

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Identifiers

PMID: 37400794
DOI: 10.1186/s12944-023-01858-4
PMCID: PMC10316563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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