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Cysteine-rich intestinal protein 1 is a novel surface marker for human myometrial stem/progenitor cells

3 Jul 2023

Abstract excerpt

Myometrial stem/progenitor cells (MyoSPCs) have been proposed as the cells of origin for uterine fibroids, but the identity of the MyoSPC has not been well established. We previously identified SUSD2 as a possible MyoSPC marker, but the relatively poor enrichment in stem cell characteristics of SUSD2+ over SUSD2- cells compelled us to find better markers. We combined bulk RNA-seq of SUSD2+/- cells with single...

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PMID: 37400623
DOI: 10.1038/s42003-023-05061-0

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