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Cysteine-rich intestinal protein family: structural overview, functional diversity, and roles in human disease

21 Mar 2025

Abstract excerpt

The cysteine-rich intestinal protein (CRIP) family, including CRIP1, CRIP2, and CRIP3, is a subfamily of the highly conserved Lin-1, Isl1, Mec3/double zinc finger protein family that exhibits diverse biological functions. The CRIP family is known to play an important role in cellular epithelial-mesenchymal transition, cell death, and tumor progression and participate in multiple signaling pathways. This article...

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PMID: 40118853
DOI: 10.1038/s41420-025-02395-y

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