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Article

Localization of EGFR Mutations in Non-small-cell Lung Cancer Tissues Using Mutation-specific PNA-DNA Probes.

Cancer genomics & proteomics - 1 Jan 2000

Shigeto Hajime, Miyata Haruo, Ashizawa Tadashi, Iizuka Akira, Kikuchi Yasufumi, Hozumi Chikako, Maeda Chie, Yamaguchi Ken, Yamamura Shohei, Akiyama Yasuto

Abstract excerpt

BACKGROUND/AIM: Epidermal growth factor receptor (EGFR) signaling inhibitors are potent therapeutic agents for EGFR-mutant non-small-cell lung cancer, but the effects of such inhibitors on the localization of EGFR mutations in tumor tissues remain to be elucidated. Thus, a simple and efficient technology for the detection of mutations in tumor tissue specimens needs to be developed. MATERIALS AND METHODS: Using...

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Identifiers

PMID: 37400147
DOI: 10.21873/cgp.20389
PMCID: PMC10320556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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