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Article

Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer.

Journal of translational medicine - 18 Dec 2010

Simonetti Sara, Molina Miguel Angel, Queralt Cristina, de Aguirre Itziar, Mayo Clara, Bertran-Alamillo Jordi, Sanchez José Javier, Gonzalez-Larriba Jose Luis, Jimenez Ulpiano, Isla Dolores, Moran Teresa, Viteri Santiago, Camps Carlos, Garcia-Campelo Rosario, Massuti Bartomeu, Benlloch Susana, Ramon y Cajal Santiago, Taron Miquel, Rosell Rafael

Abstract excerpt

BACKGROUND: Immunohistochemistry (IHC) with mutation-specific antibodies may be an ancillary method of detecting EGFR mutations in lung cancer patients. METHODS: EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non-small-cell lung cancer (NSCLC) cell lines an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21167064
DOI: 10.1186/1479-5876-8-135
PMCID: PMC3016260

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21167064-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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