Article
Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2010
Kitamura Atsuko, Hosoda Waki, Sasaki Eiichi, Mitsudomi Tetsuya, Yatabe Yasushi
Abstract excerpt
PURPOSE: Patients with mutations of epidermal growth factor receptor (EGFR) receive more benefit from EGFR-tyrosine kinase inhibitor treatment. However, usually such treatment is used to treat advanced lung cancer and only small biopsy samples are available for mutational analysis. We used immuno...
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