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Article

Rational design of an influenza-COVID-19 chimeric protective vaccine with HA-stalk and S-RBD

3 Jul 2023

Abstract excerpt

Highly contagious respiratory illnesses like influenza and COVID-19 pose serious risks to public health. A two-in-one vaccine would be ideal to avoid multiple vaccinations for these diseases. Here, we generated a chimeric receptor binding domain of the spike protein (S-RBD) and hemagglutinin (HA)-stalk-based vaccine for both SARS-CoV-2 and influenza viruses. The S-RBD from SARS-CoV-2 Delta was fused to the...

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PMID: 37394992
DOI: 10.1080/22221751.2023.2231573

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