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Epigenome-wide association study identifies Vogt-Koyanagi-Harada disease-associated DNA methylation loci in Chinese.

Experimental eye research - 1 Aug 2023

Su Guannan, Du Liping, Yu Hongsong, Li Minghui, Huang Ruocheng, Yang Xiaonan, Wang Detao, Wang Qing, Yang Peizeng

Abstract excerpt

DNA methylation is one of the important epigenetic mechanisms for modulating gene expression. By performing a genome-wide methylation association analysis of whole peripheral blood from 60 Vogt-Koyanagi-Harada disease (VKH) patients and 60 healthy controls, we depicted the global DNA methylation status of VKH disease. Further pyrosequencing validation in 160 patients and 159 controls identified 3 aberrant CpG...

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PMID: 37394087
DOI: 10.1016/j.exer.2023.109553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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