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Biallelic mutations in CFAP65 lead to severe asthenoteratospermia due to acrosome hypoplasia and flagellum malformations

14 Aug 2019

Abstract excerpt

Background The genetic causes for most male infertility due to severe asthenozoospermia remain unclear. Objective Our objective was to identify unknown genetic factors in 47 patients with severe asthenozoospermia from 45 unrelated Chinese families. Methods We performed whole exome sequencing of 47 individuals with severe asthenozoospermia from 45 unrelated families. Mutation screening was performed in a control...

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PMID: 31413122
DOI: 10.1136/jmedgenet-2019-106031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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