Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Patients with MMAF induced by novel biallelic CFAP43 mutations have good fertility outcomes after intracytoplasmic sperm injection.

Asian journal of andrology - 1 Sept 2023

Ma Jing, Long Shun-Hua, Yu Hai-Bing, Xiang Ye-Zhou, Tang Xiang-Rong, Li Jia-Xun, Liu Wei-Wei, Han Wei, Jin Rong, Huang Guo-Ning, Lin Ting-Ting

Abstract excerpt

As a specific type of asthenoteratozoospermia, multiple morphological abnormalities of the sperm flagella (MMAF) is characterized by composite abnormalities, including absent, short, coiled, angulation, and irregular-caliber flagella. Mutations in cilia- and flagella-associated protein 43 ( CFAP43 ) are one of the main causative factors of MMAF established to date. To identify whether there are other CFAP43...

Topics

Humans
Male
Sperm Injections, Intracytoplasmic
Female
Mutation
Sperm Tail
Adult
Pregnancy
Asthenozoospermia
Infertility, Male
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microtubule Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 36960497
DOI: 10.4103/aja2022118
PMCID: PMC10521949

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patients with MMAF induced by novel biallelic CFAP43 mutations have good fertility outcomes after intracytoplasmic sperm injection.PMID 36960497Read ↗

Novel biallelic CFAP43 mutations induce MMAF with mitochondrial abnormalities and successful ICSI outcomes.Semantic proximity Read ↗

Novel Mutations in CFAP44 and CFAP43 Cause Multiple Morphological Abnormalities of the Sperm Flagella (MMAF).Semantic proximity Read ↗

Novel biallelic loss-of-function mutations in CFAP43 cause multiple morphological abnormalities of the sperm flagellum in Pakistani familiesSemantic proximity Read ↗

Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella.Semantic proximity Read ↗

A novel variant in CFAP69 causes asthenoteratozoospermia with treatable ART outcomes and a literature review.Semantic proximity Read ↗

Biallelic mutations in CFAP54 cause male infertility with severe MMAF and NOA.Semantic proximity Read ↗

A novel mutation in CFAP47 causes male infertility due to multiple morphological abnormalities of the sperm flagella.Semantic proximity Read ↗

CFAP74 Variants Could Cause Male Infertility With the Asthenoteratozoospermia Phenotype.Semantic proximity Read ↗

Biallelic mutations of CFAP58 are associated with multiple morphological abnormalities of the sperm flagella.Semantic proximity Read ↗

Bi-allelic Loss-of-function Variants in CFAP58 Cause Flagellar Axoneme and Mitochondrial Sheath Defects and Asthenoteratozoospermia in Humans and Mice.Semantic proximity Read ↗

A novel recurrent mutation in CFAP47 causes male infertility with asthenoteratozoospermiaSemantic proximity Read ↗

Novel homozygous CFAP69 mutations in humans and mice cause severe asthenoteratospermia with multiple morphological abnormalities of the sperm flagellaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.