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Novel homozygous CFAP69 mutations in humans and mice cause severe asthenoteratospermia with multiple morphological abnormalities of the sperm flagella

10 Nov 2018

Abstract excerpt

Background Male infertility is a major issue of human reproduction health. Asthenoteratospermia can impair sperm motility and cause male infertility. Asthenoteratospermia with multiple morphological abnormalities of the flagella (MMAF) presents abnormal spermatozoa with absent, bent, coiled, short and/or irregular-calibre flagella. Previous studies on MMAF reported that genetic defects in cilia-related genes (eg,...

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PMID: 30415212
DOI: 10.1136/jmedgenet-2018-105486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Novel homozygous CFAP69 mutations in humans and mice cause severe asthenoteratospermia with multiple morphological abnormalities of the sperm flagellaPMID 30415212Read ↗

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