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Article

Development of antisense peptide-peptide nucleic acids against fluoroquinolone-resistant Escherichia coli.

The Journal of antimicrobial chemotherapy - 2 Aug 2023

Kim Se Kye, Lee Jun Bong, Lee Hyung Tae, Han Dalmuri, Yoon Jang Won

Abstract excerpt

BACKGROUND: Fluoroquinolones (FQs) are potent and broad-spectrum antibiotics commonly used to treat MDR bacterial infections, but bacterial resistance to FQs has emerged and spread rapidly around the world. The mechanisms for FQ resistance have been revealed, including one or more mutations in FQ target genes such as DNA gyrase (gyrA) and topoisomerase IV (parC). Because therapeutic treatments for FQ-resistant...

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Identifiers

PMID: 37390375
DOI: 10.1093/jac/dkad203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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