Article
Inhibition of Growth and Gene Expression by PNA-peptide Conjugates in Streptococcus pyogenes
1 Jan 2013
Abstract excerpt
While Streptococcus pyogenes is consistently susceptible toward penicillin, therapeutic failure of penicillin treatment has been reported repeatedly and a considerable number of patients exhibit allergic reactions to this substance. At the same time, streptococcal resistance to alternative antibiotics, e.g., macrolides, has increased. Taken together, these facts demand the development of novel therapeutic...
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