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Article

Parkinson's disease - genetic cause.

Current opinion in neurology - 1 Aug 2023

Cherian Ajith, K P Divya, Vijayaraghavan Asish

Abstract excerpt

PURPOSE OF REVIEW: Our knowledge of the genetic architecture underlying Parkinson's disease has vastly improved in the past quarter century. About 5-10% of all patients suffer from a monogenic form of Parkinson's disease. RECENT FINDINGS: Mutations in autosomal dominant genes (e.g. SNCA, LRRK2, VPS35) or autosomal recessive genes (e.g. PRKN, PINK1, DJ-1) can cause genetic Parkinson's disease. Recessive DNAJC6...

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PMID: 37366140
DOI: 10.1097/WCO.0000000000001167

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