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Article

The synergistic interaction between ACE and TMPRSS2 polymorphisms increases the risk of severe COVID-19.

PloS one - 1 Jan 2026

Bayaraa Odonchimeg, Ganbold Chimedlkhamsuren, Byambadorj Bayarlakh, Battulga Zolzaya, Dashtseren Ichinnorov, Jav Sarantuya

Abstract excerpt

Within a few years after the pandemic outbreak, several of evidence have found to suggest that the genetic factors influence the severity and mortality rate of COVID-19. In particular, the identification of genetic markers that increase the risk of severe or critical COVID-19 is important for public health management during the pandemic. By August 2021, 88.9% of Mongolian population had been vaccinated....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 41734172
DOI: 10.1371/journal.pone.0343590
PMCID: PMC12931805

Genes

ACE
TMPRSS2
ACE2
NR3C1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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