Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gastroesophageal reflux disease increases predisposition to severe COVID-19: Insights from integrated Mendelian randomization and genetic analysis.

Annals of human genetics - 1 Jan 2025

Pan Jingjing, Li Jianhua

Abstract excerpt

OBJECTIVE: This study aims to investigate the potential causal relationship, shared genomic loci, as well as potential molecular pathways and tissue-specific expression patterns between gastroesophageal reflux disease (GERD) and the risk of hospitalized/severe 2019 coronavirus disease (COVID-19). METHODS: We employed linkage disequilibrium score regression and bidirectional Mendelian randomization (MR) analysis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19
Share to Gastroesophageal Reflux
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to SARS-CoV-2

Source

Open in PubMed Open full text

Identifiers

PMID: 39530352
DOI: 10.1111/ahg.12584
PMCID: PMC11650540

Genes

BCL11A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gastroesophageal reflux disease increases predisposition to severe COVID-19: Insights from integrated Mendelian randomization and genetic analysis.PMID 39530352Read ↗

Assessing the genetic relationship between gastro-esophageal reflux disease and risk of COVID-19 infection.Semantic proximity Read ↗

Host Genetic Factors, Comorbidities and the Risk of Severe COVID-19.Semantic proximity Read ↗

Assessing the causal relationship between COVID-19 and post-COVID-19 syndrome: A Mendelian randomisation study.Semantic proximity Read ↗

Unraveling the causality between gastroesophageal reflux disease and increased cancer risk: evidence from the UK Biobank and GWAS consortia.Semantic proximity Read ↗

Causal effects of COVID-19 on cancer risk: A Mendelian randomization study.Semantic proximity Read ↗

The impact of COVID-19 on pulmonary, neurological, and cardiac outcomes: evidence from a Mendelian randomization study.Semantic proximity Read ↗

Gastroesophageal reflux disease and the risk of respiratory diseases: a Mendelian randomization studySemantic proximity Read ↗

A meta‐analysis of reflux genome‐wide association studies in 6750 Northern Europeans from the general populationSemantic proximity Read ↗

Causal Associations Between Ulcerative Colitis and COVID-19: A Bidirectional Mendelian Randomization StudySemantic proximity Read ↗

The role of gene polymorphisms in the occurrence of gastroesophageal reflux disease: A systematic review and meta-analysis of genetic association studies.Semantic proximity Read ↗

Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseasesSemantic proximity Read ↗

A Mendelian randomization study to assess the genetic liability of gastroesophageal reflux disease for cardiovascular diseases and risk factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.