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Article

Host Genetic Factors, Comorbidities and the Risk of Severe COVID-19.

Journal of epidemiology and global health - 1 Jun 2023

Zhu Dongliang, Zhao Renjia, Yuan Huangbo, Xie Yijing, Jiang Yanfeng, Xu Kelin, Zhang Tiejun, Chen Xingdong, Suo Chen

Abstract excerpt

BACKGROUND: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was varied in disease symptoms. We aim to explore the effect of host genetic factors and comorbidities on severe COVID-19 risk. METHODS: A total of 20,320 COVID-19 patients in the UK Biobank cohort were included. Genome-wide association analysis (GWAS) was used to identify host genetic factors...

Topics

Humans
COVID-19
SARS-CoV-2
Genetic Predisposition to Disease
Genome-Wide Association Study
Comorbidity
Membrane Transport Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37160831
DOI: 10.1007/s44197-023-00106-3
PMCID: PMC10169198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-37160831-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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