Article
Determining host factors contributing to disease severity in a family cluster of 29 hospitalized SARS-CoV-2 patients: Could genetic factors be relevant in the clinical course of COVID-19?
Journal of medical virology - 1 Jan 2021
Ikitimur Hande, Borku Uysal Betul, Cengiz Mahir, Ikitimur Barış, Uysal Harun, Ozcan Erkan, Islamoglu Mehmet Sami, Seyhan Serhat, Yavuzer Hakan, Yavuzer Serap
Abstract excerpt
In this study, we report a large family cluster consisting of 29 genetically related patients hospitalized with coronavirus disease-2019 (COVID-19). We sought to determine the clinical characteristics relevant to the clinical course of COVID-19 by comparing the family cluster to unrelated patients with SARS-CoV-2 infection so that the presence of potential determinants of disease severity, other than traditional...
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